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HomeBlogsTypes of Bottle Cap Liners Available at ILT
Assorted ILT bottle caps, cap liners, septa, and laboratory vials

Bottle cap liners do more than create a seal. Whether you’re packaging chemicals, pharmaceuticals, or laboratory samples, the right liner helps protect your product, maintain quality during storage and shipping, and meet your application’s performance requirements. Different liner materials and constructions offer different sealing properties, chemical resistance, and performance characteristics.

Common Types of Bottle Cap Liners and Their Best Uses

The right bottle cap liner for you depends on your product, packaging, and performance requirements.

Laboratory sample bottles and vials with screw and crimp caps
Liner TypeBest ForKey Benefit
FoamGeneral-purpose packaging, dry goods, some liquidsEconomical and resealable
Silicone/PTFEChemical, pharmaceuticals, chromatographyGood chemical resistance, resealable, and pierceable
Butyl/PTFEChromatographyLow permeability, pierceable
InductionFood, beverages, pharmaceuticalsTamper evidence and extended shelf life

Foam liners are commonly made from polyethylene (PE) or F217. Silicone/PTFE liners combine a PTFE backing on a silicone liner for improved chemical compatibility. Butyl/PTFE liners combine PTFE backing with a butyl material for reduced permeability. Induction liners use multiple layers, including foil and polymer coatings, to create a tamper-evident seal when induction sealed.

Factors to Consider When Choosing a Bottle Cap Liner

When selecting a bottle cap liner, consider the following questions:

  • What type of product are you packaging, such as a liquid, powder, or solid?
  • Does your product require protection from moisture, oxygen, or contaminants?
  • Will the package need tamper-evident protection?
  • Is the liner compatible with your product’s chemical composition?
  • Should the package be easy to reseal after opening?

Answering these questions can help narrow your options and ensure the liner performs as intended throughout storage, shipping, and use.

Plastic bottles with assorted bottle caps and closures for laboratory and chemical packaging

ILT Bottle Cap Liner Comparison Table

Use the table below as a starting point to identify the liner material and ILT product family that best fits your application.

ApplicationRecommended Liner MaterialWhy It’s RecommendedRecommended ILT Product
Environmental Sampling & TestingSilicone/PTFEExcellent chemical resistance and reliable sample integrity for
environmental analyses. PFAS-specific options are also available.
24mm Bonded Screw Caps
Gas Chromatography (GC)Silicone/PTFELow bleed characteristics and excellent resealing for repeated
injections.
Press-Fit Secure™ Caps
LC/HPLC & LC-MSLCMS Grade Silicone/PTFEMinimizes extractables and contamination for high-sensitivity
analyses.
LC Clean Caps
Chemical PackagingSilicone/PTFEBroad chemical compatibility and dependable sealing for aggressive
chemicals.
20mm Screw Caps
Clinical DiagnosticsSilicone/PTFEHelps maintain sample integrity while supporting repeated punctures
during testing.
13mm Bonded Screw Caps,
15mm Welded Caps
Headspace AnalysisButyl/PTFE or Silicone/PTFEProvides a secure seal for volatile compounds and withstands elevated
headspace temperatures.
20mm Crimp Caps,
18mm Steel Screw Caps
Solid-Phase Microextraction (SPME)Blue Silicone/ White PTFEOffers users the ability to use one cap and septa for multiple
applications including SPME and Dynamic and Static Headspace
techniques.
SPME Micro Center Liner

Customization Options in Bottle Cap Liners

Once you’ve selected the right liner material, many liner features can be customized to meet your packaging requirements, including:

  • Size
  • Thickness
  • Material
  • Printing
  • Venting
  • Perforation
  • Tamper-evident features
  • Child-resistant designs
Crimp caps with PTFE-lined septa, glass vial, and syringe needle

How Cap Liners Affect Sealing Performance

A bottle cap liner’s sealing performance depends on more than just the liner material. Thickness, compatibility with the product, and the fit between the liner, cap, and container all influence seal quality.

A liner that is too thin may not provide adequate protection, while one that is too thick may interfere with proper sealing. Chemical compatibility is equally important, as some liner materials may react with certain products or solvents. Selecting a liner designed for both your product and packaging system helps maintain product integrity throughout storage and transportation.

Need Help Choosing a Bottle Cap Liner?

ILT is a U.S.-based cap liner manufacturer offering a variety of septa in multiple materials, sizes, and configurations. Our cap liners and seals are trusted across the chromatography, headspace, environmental, chemical packaging, and clinical diagnostic industries. 

If you’re unsure which liner is right for your application, connect with one of our laboratory packaging experts to identify the best option based on your product and packaging requirements.

Learn more about ILT, the world leader in manufacturing seals and septa.