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HomeBlogsILT Pharma-Fix vs Pharma-Fix II™ Septa Comparison Table
ILT cap with Pharma-Fix septa

Choosing the right septa can affect sample integrity, chemical compatibility, and overall laboratory performance. Use the comparison table below to evaluate the key differences between ILT’s Pharma-Fix and Pharma-Fix II™ septa, including materials, PTFE coverage, temperature range, and application suitability, so you can select the best option for your workflow.

Characteristic Pharma-Fix Pharma-Fix II™
Septa Material Gray Butyl/Natural PTFE Disc Dark Gray Silicone/Natural PTFE
Crimp Type: Available Sizes & Configurations 20mm Aluminum
20mm Silver Steel
20mm Bi-Metal
20mm Pressure Release
13mm Aluminum
13mm Silver Steel
13mm Aluminum Tear Off Seal
20mm Aluminum
20mm Silver Steel
20mm Bi-Metal
20mm Pressure Release
13mm Aluminum
13mm Silver Steel
13mm Aluminum Tear Off Seal
PTFE Center PTFE disc (does not go to edge) Full face PTFE coating (edge to edge)
Chemical Compatibility Moderate High
Temperature Range -20°C to 130°C -65°C to 210°C
Bleed/Extractables Performance Low-Bleed Low-Bleed
Needle Penetration Performance Good Excellent
Sample Protection Limited PTFE barrier Enhanced PTFE barrier
Primary Applications Headspace analysis, chromatography, pharmaceutical testing,
environmental
Headspace analysis, chromatography,
pharmaceutical testing, environmental
ILT cap with Pharma-Fix II™ septa

Find the Right Septa for Your Application

Whether you’re supporting pharmaceutical research, environmental testing, or routine chromatography workflows, ILT can help you choose the right septa for your performance requirements. Contact our team to discuss your application or request additional product information.

Learn more about ILT, the world leader in manufacturing seals and septa.