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HomeBlogsILT Pharma-Fix vs Pharma-Fix II™ Septa Comparison Table
ILT cap with Pharma-Fix septa

Choosing the right septa can affect sample integrity, chemical compatibility, and overall laboratory performance. Use the comparison table below to evaluate the key differences between ILT’s Pharma-Fix and Pharma-Fix II™ septa, including materials, PTFE coverage, temperature range, and application suitability, so you can select the best option for your workflow.

CharacteristicPharma-FixPharma-Fix II™
Septa MaterialGray Butyl/Natural PTFE DiscDark Gray Silicone/Natural PTFE
Crimp Type: Available Sizes & Configurations20mm Aluminum
20mm Silver Steel
20mm Bi-Metal
20mm Pressure Release
13mm Aluminum
13mm Silver Steel
13mm Aluminum Tear Off Seal
20mm Aluminum
20mm Silver Steel
20mm Bi-Metal
20mm Pressure Release
13mm Aluminum
13mm Silver Steel
13mm Aluminum Tear Off Seal
PTFECenter PTFE disc (does not go to edge)Full face PTFE coating (edge to edge)
Chemical CompatibilityModerateHigh
Temperature Range-20°C to 130°C-65°C to 210°C
Bleed/Extractables PerformanceLow-BleedLow-Bleed
Needle Penetration PerformanceGoodExcellent
Sample ProtectionLimited PTFE barrierEnhanced PTFE barrier
Primary ApplicationsHeadspace analysis, chromatography, pharmaceutical testing,
environmental
Headspace analysis, chromatography,
pharmaceutical testing, environmental
ILT cap with Pharma-Fix II™ septa

Find the Right Septa for Your Application

Whether you’re supporting pharmaceutical research, environmental testing, or routine chromatography workflows, ILT can help you choose the right septa for your performance requirements. Contact our team to discuss your application or request additional product information.

Learn more about ILT, the world leader in manufacturing seals and septa.